![]() This striking level of comorbidity has suggested that the relationship between CP and sleep may be bidirectional. In the United States, about 63% of CP patients have reported insomnia and were three times more likely to be diagnosed with insomnia. ![]() Insomnia, a common form of sleep disorder in CP patients, may directly lead to poor long-term results by affecting several aspects of the pathophysiology and psychosocial function of CP patients. Reportedly, the majority of patients with CP report poor sleep quality. In addition, CP has been ranked the top cause of impacting the quality of life and shortening life-year in people, ahead of recognized depression, anxiety disorders, high blood pressure, and coronary heart disease. It is estimated that the annual cost of CP treatment and care in the United States is approximately $650 billion. CP exerts tremendous pressure not only on individuals and families, but also on health systems and social economy. According to statistics, the incidence of CP in adults is about 10% to 25%, and the prevalence of CP is increasing as the population ages. IntroductionĬhronic pain (CP), is defined as pain that is present for at least three months (International Association for the Study of Pain ). Due to the low quality and small sample size of the included studies, more rigorously designed RCTs with high quality and large sample size are recommended in future. Acupuncture therapy is an effective and safe treatment for CPRI, and this treatment can be recommended for the management of patients with CPRI. And there was no significant difference in adverse events (OR =1.73, 95%CI =, P =0.09) between the two groups. In addition, meta-analysis demonstrated that acupuncture group was superior to control group in debasing PSQI score (MD = -2.65, 95%CI =, P = 0.0001) and VAS score (MD = -1.44, 95%CI =, P < 0.00001). The pooled analysis indicated that acupuncture treatment was significantly better than control group in improving effective rate (OR = 8.09, 95%CI =, P < 0.00001) and cure rate (OR = 3.17, 95%CI =, P < 0.00001), but subgroup analysis showed that there was no statistically significant difference between acupuncture and sham acupuncture in improving cure rate (OR =10.36, 95% CI, P=0.12) based on one included study. A total of nine studies involving 944 patients were enrolled. ![]() Statistical analyses were conducted by RevMan 5.3 software. ![]() Two reviewers screened each study and extracted data independently. Randomized controlled trials (RCTs) were included if acupuncture was compared to sham acupuncture or conventional drug therapies for treating CPRI. Seven electronic databases were searched from inception to December 2018. The purpose of this study was to evaluate the efficacy of acupuncture for CPRI. However, the efficacy of acupuncture for CPRI is uncertain. Acupuncture has been widely used to relieve chronic pain-related insomnia (CPRI). ![]()
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